When to visit: High travel season runs May–Sep.
Peak summer (Jul–Aug) can be very hot and humid, while winter (Nov–Feb) is cold and wet. Important annual events and holidays include Holy Week and Easter (Mar/Apr, dates vary), the Feasts of Saints Peter Paul (Jun 29) and Christmas Day (Dec 25). Also, The Vatican Museums are closed on several major holidays.

7 Days Itinerary for travel to Vatican City (Holy See)
1. Spend at Rome for 4 days – Drive to Vatican City – 20 minutes
Rome, Italy’s capital, is a sprawling, cosmopolitan city with nearly 3,000 years of globally influential art, architecture and culture on display. Ancient ruins such as the Forum and the Colosseum evoke the power of the former Roman Empire. Vatican City, headquarters of the Roman Catholic Church, has St.

2. Spend at Vatican City 1 day – Train to Pompeii – 2.5 hours (or 2.5 hours by car)
Vatican City, a city-state surrounded by Rome, Italy is the headquarters of the Roman Catholic Church. It’s home to the Pope and a trove of iconic art and architecture. Its Vatican Museums house ancient Roman sculptures such as the famed “Laocoön and His Sons” as well as Renaissance frescoes in the Raphael Rooms and the Sistine Chapel, famous for Michelangelo’s ceiling.

3. Spend at Vatican Pompeii 1 day – Drive to Naples – 30 minutes
Pompeii is a vast archaeological site located in southern Italy’s Campania region. Once a thriving and sophisticated Roman city, Pompeii was buried in meters of ash and pumice after the catastrophic eruption of Mount Vesuvius in 79 A.D. Near the coast of the Bay of Naples, the well-preserved site features excavated ruins that visitors can freely explore.

4. Spend at Vatican Naples 1 day 
Naples, a city in southern Italy, sits on the Bay of Naples. Nearby is Mount Vesuvius, the still-active volcano that destroyed nearby Roman town Pompeii. Dating to the 2nd millennium B.C., Naples has centuries of important art and architecture. The city’s cathedral, the Duomo di San Gennaro, is filled with frescoes.